An illness that causes someone to believe that they are a large trout, and therefore engage in large trout-related activities, such as swimming up waterfalls and spawning. Large Trout Syndrome can be contracted via contact with fairly small trout that wish they were larger.
Friend: I like your shirt, Craig.
Craig: GLUG GLUG GLRBBSHHH GLUUUUH
Friend: Uh, oh, Craig, you've caught Large Trout Syndrome!
Craig: GLRSHHHHH GLUG GLRSHH GLUUURG
Craig: GLUG GLUG GLRBBSHHH GLUUUUH
Friend: Uh, oh, Craig, you've caught Large Trout Syndrome!
Craig: GLRSHHHHH GLUG GLRSHH GLUUURG
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