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Sis is the all around language for "Girl." It could also be short for sister. However, when you use sis, it could range from high to low with the meaning behind it. In this case, this is how we refer to our homegirls when we see them, or when responding to a question that has far more beyond just a 'yes' or a 'no'.
Sis, she has no idea
Sis, lemme call you back ! He's about to walk in.
Nah sis, He's for EVERYBODY
Sis! it's wayyyyy more to the story!
Sis, It's all love, but that ain't it!
Sis by TheWordSis.com January 24, 2019
Related Words
A commonly used word, mostly by females. Referring to a close friend or a shortened version of “sister”. Some could say this is “basic” and “overused” by more than half the internet. Someone who would use this word would probably:
1. Watch Shane Dawson
2. Say “tea”, “love that”, “queen” a lot
3. Make jokes about hating themselves
4. Bring up their depression randomly
5. Get into online fights in random discord servers
6. Wear thrift clothes
7. Have “aesthetic” things
8. Be sensitive
9. Feel the need to drink Starbucks even though they don’t like it
10. Wear adidas and giant hoodies
And the list could go on...
“Hey, sis! How are ya?”
“Omg! Spill the tea, sis.”
“I got some tacossss sisss:D”
“Sis, just stop.”
“Sis, you ain’t cool.”
“Hunny, you needa chill, sis...”
“Sis got some issues”
“Finna slap a bish, sis angry>:(“
“Shhh! Sis imma kill you”
Sis by XxcloudyxX February 15, 2019
After Debbi saw her boyfriend kissing Jane she was sis
Sis by Teen advisor March 16, 2019
Word used by bitchy Twitter Stans in a usually rude context, who think that they are top shit. These Stans are usually female, and tend to overuse words such as Tea and Y’all.
Twitter Stan: Sis..
Me: You know, I’m just about done with your shit, “JunkookFangirl97”.
Sis by MeganTheCreator April 2, 2019
something you call a girl if you have a close relationship with them
sis he is cute

sis watch out
sis by madmeeps May 2, 2019
A acronym for "she is self".
Look at her, sis is beautiful. Which means when you speak of Sis, Sis is yourself. It speaks on how you think and feel of yourself. Positive or negative. Talk to her nice 😘
Sis by M. Divine May 5, 2019