up the duff

To be pregnant.

It was very embarrssing for Kevin when he got Peggy up the duff, but it served him right for trying to save money by using a flak jacket.

by Dunky Oggins December 7, 2003

DUFF cocktail

a drink spiked with roofies and viagra used by the DUFF(designated ugly fat friend) in order to get laid.

"dude dont drink that its a DUFF cocktail." "i woke up with a headace and a raging boner next to a WHALE, It must have been the Duff Cocktail."

by [THE]fixer5588 March 15, 2010

Up the duff

Pregnant, usually unplanned.

She's up the duff and really confused right now.

by Tsee October 31, 2006

pulling a duffy

Your at the bar/event with your friends and you leave without warning or saying goodbye. AKA disappearing like Kevin Duffy

Where did JR go? dont know is he pulling a duffy

by SpecialDDs0n November 14, 2014

Mrs. Duffy

That bitch of a principal who thinks she rules the world even though she has only been principal for less than a year.

Person 1: Did you see Mrs. Duffy
Person 2: Yeah she yelled at me because she was late to a meeting

by CoolioKiddio May 19, 2020

Haylie Duff

Some rich snob prettier than Hilary Duff even though IS Hilary Duff's sister. Only popular because of "popular" sister.

The imposter of Britney Spears, Jamie Lynn Spears.

by Janice January 4, 2005

the duff

the Designated, Ugly, Fat, Friend. Everyone has one in their group of friends. shes the easiest person to talk to in the group, shes the one to go to when a guy needs to find out where the fit girl in the squad likes to eat out at.

shes the DUFF in our squad

by Trafford112 April 11, 2015