issuzizationz 

Issues - problems
Issuzizationz - Serious issues (problems)

Person #1: I'm so hungry I could resort to canibalism.

Person #2: You have issuzizationz

issuzizationz by PD7 December 9, 2008

Issce 

The name of an absolute loser. Most likely a pokimane simp (Tier 3)

See that guy? I heard his name is ISSCE, WHAT A SIMP.

Issce by peyz November 13, 2020

Issey Ward

A type of small girl who sleeps around for ket.

oh my god, that cow is acting really like an Issey Ward today

Issey Ward by inshalllllahhhsuiiiii November 22, 2021

Isseysnkn 

Isseysnkn not a lot of followers but a kind heart “hey do you follow isseysnkn on tiktok?” “No who is she?” Huh you don’t know?”shes super kind go check her out!”

Isseysnkn not a lot of followers but a kind heart “hey do you follow isseysnkn on tiktok?” “No who is she?” Huh you don’t know?”shes super kind go check her out!”

Isseysnkn by Isseysnkn February 10, 2022

Dirty Issie 

To be f*cked in the ears on both sides by two different people.

"Me and my mate gave this girl a dirty issie yesterday night, her ears are so soft."

Dirty Issie by currently shitting <3 uwu October 4, 2021

issel 

extremely cold

Yo, ike, i busted out of house and started chasing him but it was issel as a mug and i ran beck in.

issel by Benny May 2, 2003

mommy issues 

When someone can't figure out why they need approval from a strong woman. They a slut for Mommy.

Mommy issues = Please Mommy, please

mommy issues by HeteroBoySlut June 19, 2019