Glyceraldehyde Goofball

So, I think I worked this out. It's mentioned in a scene in PLL (Pretty Little Liars) S3E16, and means that Toby is Spencer's sweet drug that makes her delusional, because Glyceraldehyde is a sweet aldose, and a Goofball is a slang term for a Barbiturate.
(See also Goofball)

"You're my Glyceraldehyde Goofball"
"Erm. What?"
"My sweet sweet drug!"
"Right..."

by the__sp00ned March 6, 2015

goofball

Mixing Methamphetamine and Heroin for IV injection. Similar to "Speedball" which uses Cocaine and Heroin.

Dude, That goofball I slammed lastnight had me spun crazy all fucking night!

by Diacetylmorphine June 20, 2005

Goofballs

The act of inserting the entirety of one's testicles into the anus of another human being or animal.

Brandon: Hey Chad! Let's give her the goofballs!

Chad: Yeah let's do that? What about the dog!?

Brandon: Yeah! He's next.

Chad: We're such classic goofballers.

by theshizz55 November 14, 2013

goofball

one who makes goofy jokes and tends to say omg to goofy things

goofball: omg
normal ball: you're a goofball
goofball: omgomg!

by spanooj October 31, 2004

goofballin

When you shoot up meth in one arm, and heroin in the other simultaneously. Gives an almost zombie like experience.

Mom: "hey billy want some dinner?"
Billy: "UURRGHREYYYSSSNHLAKMAH"
Mom: "god dang it william are you goofballin' again?!"
Billy: "RHHEEEEEEEE"

by Ricky nards August 1, 2017

All hopped up on goofballs

When you're high on cocaine

After I did a couple lines,, man was I all hopped up on goofballs !

by RayRay's bad for you Chris... February 18, 2017

Goofball

Methamphetamine (speed or crank). Dates from the 1920's and was in frequent use up to the 60's. The term is rarely used anymore as a referrence to meth. It was called so because of the mentally dazed and weary state the user was left in after the drug wore off. The term is now used to describe the mental aftermath cokeheads and crackfiends go through after indulging.

With all the goofball JFK did, it's a wonder he didn't turn into one.

by El Moco Negro July 13, 2003