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pants runner 

Someone who aides in the pulling up of the pants in a geriatric facility. Generally only needed only when the resident is hard to handle or there has been a code brown(accident resulting in fecal matter in the pants)
Rhonda and Lori, CNAs, are changing Elsie's messy pants when they find a code brown.
Rhonda: oh no!
Elsie: I'm going to knock the hell out of you!
Lori: I think we're going to need a pants runner. (goes into the hall to find Donna to help wipe and pull up the clean pants)
pants runner by Lori January 13, 2005

Happy Runner 

It's in reference to a class Modern Warfare 2,made of of your choice of primary and secondary weapons and Marathon Pro, Lightweight Pro, and Commando Pro as your perks. Most commonly, your secondary would be a pistol with the tactical knife attachment. A Happy Runner runs around knifing people and risking the death count for kills.
Ranger is a Happy Runner on Modern Warfare online, she racks up knife kills by the second!

Mississippi River Runner

An act during a FMF threesome in which a male takes a shit down the girl's back so it runs down into the other girl's awaiting mouth.
I had this threesome last night and i gave the girls a Mississippi River Runner.

Homestar Runner 

That doofus who can't remember his lines. Ever.
www.homestarrunner.com
"There was this one time I saw Homestar Runner punch a kitten in the throat! No, seriously!"
Homestar Runner by Dan September 29, 2003

home star runner 

Too fucking cool - we here at www.babyfathead.com salute you, you asshole!
You smell of chickensoooooop

Homestar Runner 

Limbless bastard who should be beaten up by Strong Bad and Strong Mad.
Uh-oh! This does not look good for Homestar Runner!
Homestar Runner by dj gs68 April 25, 2003