Douche Nuke 

The only weapon capable of dealing with a Mega Douche, this is a put-down so powerful the offending douchebag realizes the full extent of his douchiness and is vaporized.

Did you hear the put-down Mike dropped on the Mega Douche Dickie? Total Douche Nuke! Dickie melted down completely.

Douche Nuke by speedshift September 14, 2014

sperm nuke 

Another way to say "dick."

Jo: Yo, he's totally a sperm nuke!
Bob: Why don't you say "dick" like everyone else?
Jo: Because I can!
Bob:*facepalms*

sperm nuke by MayoNinja July 19, 2016

tacktickle nuke

a highly explosive bomb

the tacktickle nuke blew up earth

tacktickle nuke by noooo moooooo names January 26, 2017

Jesus Nuke 

It's like a regular nuke, except it eradicates all sin within a 100 lightyear radius. It also destroys cringeworthy things like furry smut, cancer fandoms, etc. Also, when it explodes, Jesus comes out of the mushroom cloud.

Girl 1: Hey, have you heard of K-Pop?
Girl 2: OMG YASSS I LOVE K-POP!!!!!
Guy: DROP THE JESUS NUKE!
*Explosion punctuated with angelic choir music*

Jesus Nuke by guymanchester August 13, 2017

Schmeat Nuke 

When you hold in the nut in for prolonged periods of time, and release it.

“Hey babe it’s been a while since I’ve done anything so prepare for a schmeat nuke”

Schmeat Nuke by xXBaconOnAStick January 29, 2020

Hippo Nuke

When your mom jumps.

bro that Hippo Nuke was lit

Hippo Nuke by GlizzySock July 13, 2021

North Korea’s Nuke 

A few pieces of cardboard glued together with a radiation symbol drawn on with crayon.

Person 1: Are you afraid of North Korea’s Nuke?
Person 2: Afraid that it might give Kim Jong Un a paper cut? Not really.

North Korea’s Nuke by University of Markov May 18, 2018