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Pharmaceutical methamphetamine hydrochloride in pill form.
Biggest bang for the buck is to soak it in H20, thus extracting the active element. You get a pale yellowish solution. Tie up, IV, and hang on when the rush hits.

Disclaimer: I don't recommend doing this.
"I just scored some Desoxyn. You got gimmicks? We can get fucked up all night now!"
desoxyn by Straight Shooter October 18, 2007
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desoto jones 

5 stunning gentlemen who make cool sounds come out of musical instruments or a mouth. They live in New Jerzay.
Did you see Desoto Jones?
Yes, and my shoes fell off
desoto jones by Desoto Jones August 28, 2006
Related Words
Dezso Dezső deso desolate dezo desolation desoxyn Dezmond deason Delson
N. A state of being, a headspace or mindset.

Being "deso" suggests a wanderlust mood that blends outdoor adventure and a thirst to get respectfully wild.

It's a need to be outside, experiencing life in its rawest form.
Tyler has always been an explorer, he's so deso.
Deso by TurnieSanders June 8, 2017
Designated Driver. One who can't drink during a night out in order to drive accompanying parties safely home.
I'm the deso, deso and I'm rocking super clean so show me some love (I'm taking one for the team)
Deso by robby.sizzle February 19, 2013

desourdy 

a lineage of very hairy men from France, known for their redneck antics.
Your such a desourdy!
desourdy by fiveheadasaurus freak December 30, 2009

defsopresh 

a lame term preps use to describe things like designer shoes, designer bags, and more disgusting things like that.
prep: hey did you see my new juicy bag? it's defsopresh.
normal person: -bitchslap-
defsopresh by insertcatchynamehere January 24, 2011

desocialize 

The man was desocialized and led an hermetic life.
desocialize by uttam maharjan July 31, 2012