The feeling which one experiences after eating a large meal. Usually characterized by sluggish, drowsy, tired, or lethargic feelings.
Mark: "Wow, you just ate like three Big-Macs"
Andrew: "Yeah, the itis has really started setting in"
Andrew: "Yeah, the itis has really started setting in"
by Mark TB January 31, 2009
 Get the Itismug.
Get the Itismug. by Chissi December 19, 2014
 Get the ITYSmug.
Get the ITYSmug. That drowsy feelin u get after a big ass meal. U usually dont want to do anything or have lost the energy to do so. Recently popularized by black people
If u go over to yo grama's house and she cooks up a good meal like she always does u would get the itis from dat.
by Andre Benjamin December 31, 2007
 Get the itismug.
Get the itismug. by Pistalwhipped.net January 27, 2004
 Get the the Itismug.
Get the the Itismug. by davidsmells June 7, 2005
 Get the itymug.
Get the itymug. by Martinelli2 July 14, 2006
 Get the Itimug.
Get the Itimug. 