You me and Dupree

Definition:

Depending on intonation; referring to the third wheel, or the more the merrier!.

Phrase:

meaning to include; you, me, and the person and or people I, you, and or the situation are bound/obligated to, and or whom ever may be so inclined to participate either of free will or by circumstance.

Aaron: Dude please come to my mother's house this weekend, I don't want to go alone, I've asked my girlfriend, Ruben and you.

Me: eh why not, maybe I'll cook breakfast and we can go sledding.

You me and Dupree.

Aaron: yeah! Good idea!

Ex:2.

Jae: Dude wtf, I thought it was just supposed to be us two in this bed.

Aaron: yeah my bad, My dog likes sleeping with me.

Jae: great I have to share a bed with you, me, and Dupree

by Loupcastille January 5, 2018

The Dupree

Jerking off at any time and place (usually involves Starching Gym Socks

In the movie "You, Me & Dupree", Dupree pulled off the Dupree in one of Carl's socks.

by MOCO & P-Phat May 29, 2010

DuPree

He is a tall, athletic, darkskin, smart, and funny boy who is an amazing talker if you ever have a problem talk to Dupree he will help you with a lot of things so be grateful that you have one there’s only a few out there.

Me: hey Dupree helped my learn how to play 2k now I’m a goat like he is. Friend: I know right Dupree is the bomb We love you Dupree

by TheRealestOne456 September 7, 2020

dupie

Jake Murphy’s formal incorrect spelling of the proper word “dupey”.

“Yo that shit was so dupie cux I’m womped off these carts!

by mameetup January 8, 2020

Dupixent

Dupixent (Dupilumab) is a medication given in 300mg doses by injection. It's most commonly used to treat atopic dermatitis (eczema) and can potentially cure the rash from repeated use . Though highly effective, the injection burns like all hell. It may be injected in three areas, upper arm, middle stomach, or thigh. All are immensely painful and feel as if you are being injected with battery acid. It sucks... but it's worth it.

mother: "Don't forget honey, you have Dupixent today"
Kid: "God damn it! It hurts like hell but works like magic"

by Jessabelle1977 August 8, 2022

Harlan DuPree

Anus gargling faggot

Daniel is a Harlan DuPree

by heapsnake October 5, 2012

Cousin dupree

Someone male soliciting incestual. Illicit sex with a relative. The term comes from an old steely dan song of. The same name. The chorus/refrain in the song is: "how about a kiss from your cousin dupree?"

Lisa:I'm not going to my family reunion this year. Beds:why not? Lisa: cousin dupree!

by 4realazitgits March 5, 2021