tweakend 

the act of tweaking out on the weekend. A tweakend starts saturday night around 10 pm and ends sunday night around that time.
pick up a dub sack or a 30-sack, find a spot, party up with a couple of fat lines now and another couple of fat lines around 3 am save some to share with another. party on by going to a club, or a walkabout all night.

i be smoking a gang of kush at the skatepark on saturday that i get so much euphoria that i end up pulling a tweakend saturday night after the park closes.

tweakend by skaterjack October 5, 2006

tweaker 

tweak=freak out, jumpy, on edge.

Shell tweaked when Mike scared her.

tweaker by ATXmoneymike January 26, 2005

Tweaker 

Philadelphia's (Philly's) own slut.
The word "tweaker" is often used to describe a girl with sloppy, slut-like attributes, and is known for getting with a lot of guys. A tweak is a nicer way of calling a female a whore, and or slut, and a tweaker may get with more popular, or famous guys. The word "tweak" is also used and is just a shorter version of the word "tweaker".

Malik: Yo, did you see Vanessa with Jamal last night? Yeah, she was giving him head in the back of the party, and everyone saw...
Kyle: Yeah, I know, that girl is such a tweaker.
Malik: Smh what a tweak.

Tweaker by Olive_Garden69 October 30, 2011

tweaker flakes 

fish flakes that someone on ecstasy or meth rubs on their palms in hopes of getting the fish "high" or somehow speeding them up as fast as the users mind is going so they will keep the user occupied

I was rollin' ballzzzz last night and had to feed my fish some tweaker flakes so i wouldnt make noise and wake up my parents

tweaker flakes by sammymw February 11, 2010

Reality Tweaker 

Someone who's personal definition of reality, is stronger than the view of the general consensus. A reality tweaker is someone who percieves things correctly, but perhaps, neglects to hone in on the smaller details, that fill out the bigger picture, therein bending the facts to their own whims. It is impossible to get an accurate retelling of events from a reality tweaker, and it is difficult to convey common sense instructions, because many facts will be tweaked, and lost along the way. Never assume that a reality tweaker will understand the simplicity in what you are trying to convey. Reality tweakers are not dumb or retarded, and my surprise you ultimately by their ability to understand complex ideas as well. It is impossible to ever truely predict the actions of a reality tweaker.

Jean: Kyle what are you doing with that VHS tape?
Kyle: Well, my grandma gave me this video to watch, but I don't have a VCR, so I'm running it under the tap to soften it up so I can crack it open and watch the pictures inside. It's gonna be great!
Jean: There are no pictures inside, it's a magnetic strip!
Kyle: No, you see, the water will be polarized by the magnetic charge, and I'll run through the strip, then it'll get subliminally imprinted onto my brain, and I'll dream it next time I sleep. I've got it all figured out.
Jean: Reality Tweaker!

Reality Tweaker by p@$$ing thr.ugh January 11, 2010

tweeked 

to be forced into smiling by infectious enthusiasm and boundess energy

you've been tweeked, i was at a low until i got tweeked

tweeked by gsxrboy June 23, 2007

tweaker 

A small, long and narrow screwdriver, usually plastic, commonly used for adjustments to sensitive electronic components (coils, potentiometers etc)

"Hey Lou, pass me the tweaker, I need to make an adjustment here"

tweaker by anon-e-mouse April 11, 2005