tweaker 

one who 'tweaks balls' as in one who uses the drug methamphetamine to get amped and then shakes around and talks non-stop.

I would have asked Mary to help me study for my test but she's such a tweaker --she couldn't sit still for more than 2 minutes so that's why I got a D+

tweaker by brandon December 3, 2002

tweeked 

freaked out; scared

You tweeked me out!

tweeked by Jacob Leeson June 9, 2004

tweaker 

a whore, a promiscuous female who engages in sexual activity with a lot of people who they have no relationship with.

"man, she'll let anybody hit, she a tweaker."

tweaker by k_milly May 11, 2009

tweaker 

Someone with a methamphetamine who is usually a theif.

That fucking tweaker stole my lighter

tweaker by Dzay June 22, 2007

tweaker bitch

short, brunett, flirt whore of a chick, whos obviously a bitch and a tweaker! and she damn proud of it!

-sup stormon?
-nothing tweaker bitch, what about u?
- about to go tweak!
- hahah tweak tweak, L8r i'm gonna go smoke

tweaker bitch by stormon February 22, 2005

Tweekedly 

Doing things in a manner that Highly suggests, if not out and out proves that you use or used was too much Meth, Crack, or all of the above

Terra was tweekedly frail in the picture on the couch

Tweekedly by AcIdReIgN August 27, 2009

TWEAKER HULK 

A SUCKED UP GOOFY LOOKING TWEAKER THAT RAGES WHEN HE DOESN'T HIS FIX OF "METH"

THAT DAMN TWEAKER HULK DESTROYED MY CAR AND STOLE MY STEREO.

TWEAKER HULK by BIGGUNZ76 June 8, 2016