Harbaughs.khakis is a stupid meme page on Instagram, don’t follow him. He likes black girls way too much, and his friends often call him a white Uncle Tom. Once he even said he would lick a WNBA player’s ab sweat.
A term referring to when someone (usually a white person) is getting heated over a simple problem that isn't as big of a deal as they're making it out to be. Can be used regardless of if the person is wearing khakis or not.
"Ay, bro, don't piss your khakis, I'll pick up some rash cream later."