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.45 caliber aspirin

To shoot ones' self in the head with a .45 caliber bullet.
I'd take a .45 caliber aspirin and die a sad person before taking a class with that professor again.
by Titus1133 June 6, 2010
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Aspirin

A popular term for Acetylsalicylic Acid. In Canada and Germany, among other countries, Aspirin is a patented trademark of the local Bayer subsidiaries. Therefore, any non-Bayer products are labelled as ASA (Canadian English), AAS (Canadian French), and ASS (German). I am not making the last one up!
by DFJD May 17, 2006
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aspirin

A bullet to the brain or blow to the head. Usually to someone who's annoying. Lead medicine.

Not necessarily to kill someone but essentially doing something to either shut them up or get them to leave.
"Hey Lou, whatever happened to that loud mouth you kept out back?"
"Gave him an aspirin."
by Nova0 June 11, 2009
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Children's Aspirin

1 part Captain Morgan, 1 part orange juice. Also known as a "rum screwdriver" or a "hammer."
"Oi! Bartender! Fetch me a Children's Aspirin!"
by James Rodesiler September 25, 2007
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assortaint

Double meaning:

1. Past-tense KY podunk version of ascertained - Determined, discovered with certainty.

2. Noun - Anal or genital region of the male anatomy.
1. He assortaint that yer a dick.
2. Is that assortaint? I can't tell, but it smells like shit either way.
by Lydia McMullin November 3, 2006
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Assertained

Someone who was delayed because they were busy sitting on the toilet.
He could not answer the phone because he was temporarily assertained.
by Tranquillity Base February 8, 2022
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aspinating

Something that is fascinating from the perspective that it is incredibly aspie
"According to wikipedia conversations and such from No One Lives Forever place the game's chronology to be around the last week of September, 1967. That is aspinating."
by Tiiim June 25, 2008
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