MSF

My shoeless friend

The country girl lost her shoes ginger like; she will forever be your MSF

by Csanti September 27, 2017

MSF

My Space Friend; People you add to your profile that you call friends.

Jenny is Kirsten's newest MSF.

by Jenn W. August 3, 2007

MSF

Male Sexual Frusteration...the one week a month a guy get his chance to bitch never ending about shit

Take that women

Steve: Man that pisses me off!!!
Dan: What is wrong with you? it it MSF time?

by 2 Stale Crackers March 9, 2009

MSF

Mean Sober Friend. Someone, in a group of people drinking and having fun, that is unhappy and angry.

When a man is talking to a group of women (can be generalized to other social interactions), sometimes one woman, usually the least attractive of the group, is not getting enough attention. While everyone else is laughing and having fun, she tries to interrupt by saying, "let's go somewhere else," or "I'm tired;" or verbally attacks the male suitor. She is an MSF.

by Jerry406 November 17, 2007

MSF High

An obscure transformation fetish webcomic on DeviantArt that has incredibly deep and in-depth lore for some unexplainable reason.

"MSF High is such a weird read. On one hand, it's clearly made by and for transformation fetishists to rock their socks off to, but on the other hand the lore is actually super well written and really in-depth."

by KrimsonKatt January 13, 2022

MSF

Militaries Sans Frontiers-private military company made by Big Boss during the events of MGS: Peace Walker. Predecessor of Outer Haven.

"We've come to you-Militaries Sans Frontiers for help" MSF

by doobi January 26, 2025

msf

abbreviation of "myself"

i identify msf as kilometres per second cuz i want to km/s

by benzoganger February 20, 2024