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"MSF, huge ugly teeth, glasses and no life. Looking for one night stands or a f*ck buddy even though I'm the ugliest man on the internets."
by Mya Kumar August 06, 2007
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ACRONYM FOR MANDEM SQUAD FAM. IT IS MADE UP OF ONLY THE FINEST AND MOST CULTURED HUMAN BEINGS ON EARTH. ALL OF THEM ARE SEXY MOTHERFUCKERS WHO GET THE GYALDEM ON A DAILY BASIS. EVERYONE ON THIS EARTH WISHES TO BE ON THEIR LEVEL. THE MSF NEVER TAKE THE L. THE ONLY MOMENT THE MSF TURNS ON EACH OTHER IS ON THURSDAYS PERIOD 5. THAT'S CAUSE FOOTBALL INNIT. THE MSF NEVER SLEEP. THE MSF NEVER DIE. THE MSF IS A GIANT ORGANISATION IN WHICH SEXY MOTHERFUCKERS DICTATE THE FUTURE OF HUMANITY. THEY ARE BASICALLY THE ILLUMINATI BUT PENG. THEY ARE THE MANDEMSQUADFAM.
The MSF are sexy bois. I wish I was part of them lots SQUAD.
by ElegantYute January 26, 2019
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-Mentally sexually frustrated
-wanting sex mentally, but not physically
-usually a virgin who is feigning for sex
boy: so what chu wanna do when we chill?
(girl)anything really, but quite honestly im MSF.
boy: wha dat mean?
(girl) i mentally sexually frustrated
boy:i thought you was a virgin..
(girl) i am. in my mind i want sex badly, but physically i not feelin it as bad..
boy:lets do it! i can help ease your mind ;)

friend1:im sexually frustrated
friend2: im MSF
friend1: huh?
friend2: mentally sexually frustrated. im horny mentally
friend1: oh, im horny physically
*what have our lives come to*
by kitehigh24/7 January 30, 2010
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An annogram for Make Some Fucking Sense. Used for a time when the person you're talking to is being a dumbass.
Guy: I saw a guy with huge forceps.
Girl: Forceps?
Guy: please MSFS and tell me youre kidding
by ChocolateRain(ing Men) December 27, 2011
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Mean Sober Friend. Someone, in a group of people drinking and having fun, that is unhappy and angry.
When a man is talking to a group of women (can be generalized to other social interactions), sometimes one woman, usually the least attractive of the group, is not getting enough attention. While everyone else is laughing and having fun, she tries to interrupt by saying, "let's go somewhere else," or "I'm tired;" or verbally attacks the male suitor. She is an MSF.
by Jerry406 October 29, 2007
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The abbreviation MSF stands for "Male seeking female." This useful shorthand is used by online chat-room dwellers at random chat websites such as Omegle often in place of a greeting. By messaging MSF one clearly states to the other chatters they are a male interested in females. A female may also use the similar abbreviation FSM, or "Female seeking Male."
Stranger 1: hey MSF
Stranger 2: No way, FSM!
by Hew Shin Po January 29, 2014
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