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Sickle Cell 

Sickle Cell comes in two forms:
Sickle Cell trait Sickle Cell disease.
Sickle Cell trait is when you're a carrier of the gene. There aren't really any eminent medical concerns. There are limitations on what you should do that comes with the trait.
Sickle cell disease usually occurs when two people with Sickle Cell trait have a child. Sickle Cell disease can create major medical concerns such as blood sickling episodes and stroke.

Both come with the chance or higher susceptibility to Anemia.
Both are also hereditary. Most times it (in trait form) is found in African Americans. (1 in 500 African Americans have it, some don't know)
"Do you think this wig would give people Sickle Cell?" Chris Rock, Good Hair
Sickle Cell by girlwiththetrait October 27, 2011
Related Words

Twat sickle 

When your lady friends vaginal juices are so thick and greasy that they leave a hard coating on your erect pecker, this creates "The Twat Sickle". This is usually an undesirable ailment, so to be called one is rather rude.
(Dave) "Man, after banging Susie last night I woke up with a huge Twat Sickle!
(Joe) "You better get that thing on ice!"
Twat sickle by Dave "The Air Bus" September 22, 2008

Sicko mode

A way to describe a being in a higher state of physical or mental understanding. Also known as being on another plane of existence.
Dang when Calvin hit that shot bar in against Munson, he was inside of sicko mode.
Sicko mode by Preston Chungus January 4, 2019

Minecraft Sickness 

A common sickness experienced by builders who play Minecraft for an extended period of time, especially Survival Mode.

Some symptoms of minecraft sickness are:
-renewed fear of the dark
-urge to place torches in a dark hall
-wondering if there's any diamond under your house in real life
-urge to punch trees
-animal abuse
-putting raw pork into stove
Junkie1 and Junkie2 are going camping

1: Bro, its getting dark, we need to light some torches and put them on the trees
2: ok! (gets coal from grill and a stick)
1: no wait i already have some! (gets matches)
2: wait what we thinking! putting torches on trees is just as bad as flint and iron!
1: well if we cant have light, we have to stay up all night and make sure creepers don't get us.
2: we can still make a small fort with the wood around us (punches trees)
1: (comes to senses) oh no! we have minecraft sickness!
Derivative or diminutive of sick or ill.

A way of speaking used to indicate sickness in a cute way; amongst friends and family members (esp when small children are involved).

Sicky can be interpreted both as being physically ill, or a mentally warped idea; but the majority uses the word to describe physical illness.
It's cold outside, and I'm feeling kind of sicky today!
Sicky by Fukaface! December 16, 2010

sickover 

The feeling you get after you recover from being sick, but you still feel like shit, yet show no symptoms of the disease.
Person 1: Hey man, you down to have a kickback at your place tonight?
Person 2: Not tonight no, I just came off some crazy fever, and am feeling a bit sickover.
sickover by Hellexis November 29, 2009