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October 22

by Aye it’s nigga toe October 21, 2019
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mayfield and 22

Originally used in Grey’s Anatomy, when Alex Karev used it as an excuse for being late to surgery. Mayfield and 22 means erectile dysfunction.
Sorry I was late I was at an appointment with Mayfield and 22 and it ran late”
by Cuties🥰 January 5, 2023
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April 22

Racist joke day

*say racist jokes when not supervised
Person1: Guess what day it is (April 22)

RACIST JOKE DAY
by Xx_DirtLYfestiyle_xX April 22, 2022
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July 22

National receive an arch pic day, today is the one day where you can get 1 free arch pic
"babe where's my arch pic"
"Why do you get one"
"Because it's July 22 duhhh"
by Yk I'm Day Guy July 22, 2024
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big wood 22

by bigwood22 May 25, 2019
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Mr. 22

Usually a rabid gooner who treats females questionably by and has plenty of tonsil stones
“Yo that’s Mr. 22 didn’t he get took advantage of by Greta and DM Mimi if he should shave the nuts?”
“Ewwwww Mr. 22? Heard his breath smells like shit cuz of tonsil stones
by Reactz October 22, 2025
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December 22

National ask your friend out day!
Dude 1: Hey wanna go on a date?

Dude 2: I thought you were straight, and so am I

Dude 1: It’s December 22nd calm down!!
by thatoneawkwardpansexual December 22, 2020
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