Duff

Dumb, Ugly, Fat, friend

Oh my gosh she is such a duff..

by gamerpeeps500 August 23, 2021

duffl

every sorority's and fraternity's primary plug for anything and everything a college student needs on a daily basis.

yo my Puff just ran out
- just duffl it

by crazyfalafel9 September 11, 2021

Duffice

To get beaten up or physically assaulted, particularly by a large gang of men.

"Yo, is that man tryna catch a duffice?"

"Man's tryna catch a duffice, eh?"

"We're about to pull up on him with the duffice!"

by sasan July 5, 2021

Duff

“Designated ugly fat friend”

“Your literally a duff..”

by Goaty_boaty September 18, 2021

duffencheese

the feeling of eating ben and jerries.

duffencheese! this ben and jerries is amazing.

by bellieeboo September 18, 2021

duff

(D)esginated (U)gly (F)at (F)riend

You are a duff
We have a duff in our friend group

by huoon October 14, 2021

DUFF

Duff the DESIGNATED UGLY FAT FRIEND as a duff i would know its not fun ,sometimes u get ignored by ur friends and you feel left out

"I was a DUFF back in middle school."

by Vampie the queen October 20, 2021