Derived from the "Spidey sense" of the comic book superhero Spiderman, it is generally used to mean a vague but strong sense of something being wrong, dangerous, suspicious, a security situation.
He looked like a student, but something about his dirty shoes and the way he tried to open a locked door totally set off my Spidey sense, so I called campus security.
by JohnnyHoffa March 23, 2008
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To know someone in the biblical sense means that you have had sexual intercourse with him or her. It is a reference to the meaning of "know" in the Bible.
Man 1: What do you mean by "know in the biblical sense"?
Man 2: I've slept with her. We dated last year.
Man 2: I've slept with her. We dated last year.
by A1988 December 12, 2012
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