tweaked out 

A person typically and habitually under the influence of cocaine, methamphetamine, diacetylmorphine, and any other tweaker choice you could think of.

Bob: Hey Jimmy see that guy over there?
Jimmy: Yeah man, he's acting pretty weird.

Bob: Eh, must be tweaked out or something .
Jimmy: On the real lets keep movin.

tweaked out by Burberry Hilfiger January 16, 2016

Tweekedly-Spun 

Being beyond wasted on Crystal, Crack-Cocaine or all of the above

You could see that she was tweekedly-spun as she sizzled on the couch

Tweekedly-Spun by AcIdReIgN August 27, 2009

Tweekertalk 

When a tweeker gossips about others. Specifically about others being Rats, or paranoya concerning the police.

Your such a liar, thats tweekertalk.

Tweekertalk by Salupinyou October 8, 2010

Twecked 

Messed up, crooked

My back is all twecked out.

Twecked by Highmatetnce March 9, 2020

Tweeker 

A person who is addicted to crystal meth and undergoes great changes in personality and appearance. The biggest populations are in small towns and rural areas. The drug is incredibly cheap and easy to manufacture, so no matter where you live there is probably at least 3-4 residents in your neighborhood making it in their garage.

There are a few very easy ways to spot a tweeker.

1. Very skinny, with especially gaunt faces
2. Complete disregard for appearance. They will have dirty clothes, be unshaven, messy hair, no makeup.

3. Appear to be much older than they actually are.
4. Brown teeth, often with many missing.

5. They have red sores all over themselves, this is from picking at their skin while high.
6. They are generally very paranoid and confused.

You can see them anywhere, in a small town it's not uncommon to see a dozen in the course of a day. Generally avoid them and don't give them the impression that you have anything of value. If you see them in a retail store, they are almost 100% guaranteed to steal something.

It's a sad transition, and almost always their journey ends in prison or death.

Drive to the oldest, shadiest area of your town and observe the people walking around, you will spot some tweekers almost immediately.

Tweeker by Maximillian Van Der Mann January 23, 2011

tweekend 

to tweak out on the weekend, starting on a friday night or saturday night and ending on sunday evening depending when you crash (come down). a dub sack or a 30 sack is enough for a whole tweekend if you like snorting lines but if u like smoking, a half tina is good, OR just have enough to share with another. when the tweekend is over smoke some kush, but get some food, water, and vitamins back in ur system as it has been drained during the tweekend.

the best part of a tweekend is when it has started or is starting..

best tweekend night: warm, humid july night.

what u need for a tweekend:
backpack, change of clothes, (for a cold winter night-long pants, long sleeve shirt and long johns,and a jacket or sweater with hood, a hat. warm summer night-long pants or shorts, tshirt or tank top), shorts if it is hot, water, cash, a dub sack or bigger, a piece if u r not sketchy carrying one, a bike or a razor scooter, and a good chill spot for the night, and if ur lucky, a hookup to bring back to your chill spot. and make sure u have a lighter, and some chronic or better is good when you crash.

i pull tweekends when i smoke a gang of kush or chronic that i have so much euphoria that i feel that i can party all night.

tweekend by skaterjack October 5, 2006

tweeker 

The homeless, meth addict, usually skinny, smelly, who is riding a 10,000 racing mountain bike, dressed in rags, malnourished, at three oclock in the morning through the streets of sunnyslope, (phx az)with a 10 foot antique brass lamp over there shoulder on their way to the (meth)dope mans house to score another $20 bag, if you watch him long enough you will most likely see him look over his shoulder to see if "they" are close behind, you will likely see him stop at each and every dumpster that looks like it might have anything at all in it.

phx cop to glendale cop: anything new tonight?... (tweeker rides by on sidewalk causing officer to spill his coffee) damm tweekers! watch where you going or ill arrest your ass for ....glendale cop in response....."you mean you actually bother to arrest them? me and the boys find it so much quicker just to stop em, confiscate their drugs and let them go."

tweeker by nobody in phx June 19, 2009