.22 

A small pistol incapable of doing much damage.

Yo, put that duece(.22) down, that shit aint gon hurt nobody.

.22 by Tenty-two, or Duece May 19, 2003

22 

The number of love. When two people fall in love, the number 22 will follow you. If you see a 22, that means that the person you are in love with is thinking about you.

Listening to Love Story at 12:22 in the afternoon.

22 by 122206 January 18, 2010

22 

The age after 21 where you realize you still have another 3 years to get your shit together

Haha I'm only 22

22 by Jeri Lei August 11, 2008

22 

the number of princesses

wow look at that princess over there. he most love the number 22.

22 by theshackisbeastly August 25, 2010

22 

1) A .22 caliber handgun
2) Any rim that measures 22 inches in size
3) Slang term used for women to let you know they are prostitutes.

1) Don't tote no 22's
2) Magnum cost me 22, sat it on them 22's
3) Lil mama super thick, she say she 22

(All examples from Rick Ross' Hustlin)

22 by TheChef May 12, 2006

22 

a professional woman who knows how to please a man

At a bar, two men watch as a hot, librarian walks into view. One man looks at the other and says..."check out the 22."

22 by jjpaige July 13, 2009

22 

A sexual position depicted through numbers (like 69); meaning doggystyle (could be used for anal sex as well).

My favorite position is 22.

22 by SoLux August 15, 2008