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Internet's Down Syndrome 

A temporary condition brought on by the lack of internet connectivity and characterized by irritability, fidgeting, lack of focus, a general feeling of helplessness and occasionally exercise.
Steve: What's up with the glazed look on Meredith's face?

Brad: Well, she likes to start her day reading Perez but we have no connectivity and slipped into an acute case of Internet's Down Syndrome.
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Down's Quindrome

A condition affecting one in every 7 billion people. Symptoms include giving people second hand mental AIDS, perpetual idiocracy, inability to formulate one complete sentence, and an exponentially decreasing pass accuracy.
Wow, Down's Quindrome really hit that child hard.
Down's Quindrome by Not Quin April 21, 2017

downy strength 

The superhuman strength that is associated with people with down syndromes
Can be used to insult someone.

E.G. when lifting something, "well aye cannit believe your lifting that, must be that downy strength"
downy strength by Jimmyjuice1 December 29, 2016

Little donny's diease 

When the penis is so overlarged that you need to make a special holder for the penis so it does not get stuck in the bike chain.

downy soft 

Generally a very soft person that is not tough and too nice and lets people get away with things
When Mike stole johns phone he was being downy soft
downy soft by yeet890 March 16, 2017

Double Down's Syndrome

A sickness developed while playing Blackjack that causes you to risk all your chips constantly from doubling down.
Jim lost all of his money at the casino yesterday after getting a case of Double Down's Syndrome.
What people looking to differentiate themselves call McDonalds
I denied tims and went with donny's today in lieu of coffee
Donny's by recroad April 27, 2020