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Refering to someone with Downs Syndrome - so really should be "downsie" It is a genetic condition that is increasingly common the older the mother of a child is when she falls pregnant. Downs Sydrome is caused by non disjunction of the 21st chromosome (humans have 23 pairs of chromosomes - each parent supplies 23 chromosomes to the child getting a total of 46) which means chromosome 21 in the mother has not split like it should when making sex cells (gametes) and the child ends up with 3 copies of chromosome 21 compared to the usual 2. Some characteristics of downs syndrome include:

Poor muscle tone
Slanting eyes with folds of skin at the inner corners (called epicanthal folds)
Hyperflexibility (excessive ability to extend the joints)
Short, broad hands with a single crease across the palm on one or both hands
Broad feet with short toes
Flat bridge of the nose
Short, low-set ears
Short neck
Small head
Small oral cavity
Short, high-pitched cries in infancy

Sufferers of Downs Syndrome are ussually smaller than their normal peers and their physical and intellectual development is ussually slower.
"He looks like a downy."
"Her brother is a downy."
by [skorpion] December 09, 2004
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Jul 25 Word of the Day
A jack off buddy (from 'cum' /'come', meaning 'semen', and 'companion'); a friend that you get together with for sessions of solo or mutual masturbation
Variant of: cumpanion (from 'companion' & 'cum'); jack off buddy & wank bud & JO buddy
Similar to: fuck buddy
My bf and I used to really get it on together, but now it's just the occasional cumpadre wank
by Gladys Pipps-Knightley May 14, 2007
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2
A derogatory term for someone with downs syndrome. a insult to someone who may act like they have downs syndrome, or just a dumb fuck
(everyone) HEY JOSH U STUPID DOWNY!!
josh(downy) fuck off
by robyn the whore September 28, 2006
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3
andrew copeland is a downy and he think's bluelist loves him but unfortunately this is untrue and he has one less chromosome
by pussydandruff June 24, 2011
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5
Downy refers to someone with down syndrome, but when shortened to downy it is to be use to describe someone who is weird or says stupid shit a lot.
"Noah shut up ya fucking downy!"

"Alex is such a downy! Lol"
by SnoopdoggFromRecroom January 15, 2019
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6
slang for a person with down-syndrome
Man you are acting like a downy today.
by EeeBbb March 13, 2006
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