PCC is Pyridinium ChloroChromate (Pyridinium chlorochromate). It oxidizes primary alcohols to aldehydes and secondary alcohols to ketones. One has to be careful with the amount of water present in the reaction. If water is present, it can add to the aldehyde to create the hydrate, which could be further oxidized by a second equivalent of PCC if it is present. This is not a concern with ketones because there is no H directly bonded to C
Tony: I oxidized ethanol (100% drinking alcohol, ethyl alcohol) to ethanal (acetaldehyde, the stuff that gives you hangovers) while keeping things dry to prevent over oxidation to ethanoic acid (acetic acid, pure vinegar, final metabolite of ethanol). Then I chloromethylated thiophene to 2-(chloromethyl)thiophene. Then I condensed acetaldehyde with ethylamine to form acetaldehyde ethylimine. Then I formed a grignard reagent of 2-(methylmagnesium chloro)thiophene and reacted them in diethyl ether to form ethiopropamine (EPA). This stimulant could be used for ADHD and ADD. It makes you confident, happy, helps you remember stuff, and keeps you focused. It's weaker than Ritalin, but it's stronger than coffee.
Warning /!\: Research chemicals have not been evaluated for long term effects and is not for human consumption.
CH3CH2OH --PCC--> CH3CHO
Warning /!\: Research chemicals have not been evaluated for long term effects and is not for human consumption.
CH3CH2OH --PCC--> CH3CHO
by CognitiveFuel September 11, 2023
Baka is the Japanese word for fool. But if you say, "Que? Vaca?!" It means a "what? cow?!". Vaca is cow in Spanish. So watch them get upset and stuff.
Toshi: You Baka!
Tony: Que? Vaca!?
Toshi: uejf7@$&$*%(
*Toshi explodes
Tony: That's right! Tony sumar dos mas dos.
Tony: Que? Vaca!?
Toshi: uejf7@$&$*%(
*Toshi explodes
Tony: That's right! Tony sumar dos mas dos.
by CognitiveFuel July 10, 2023
A sleeping pill is Amitriptyline 50mg taken an hour before bed. It helps you sleep and you will even sleep in the middle of the next day for even more hours. It wears off around the third day. It's stronger than Melatonin and stronger and safer safer than Benadryl, Zzzquil, and Ambien. Only Melatonin is safer but Melatonin doesn't always work. The opposite of a sleeping pill would be a wakefulness pills like Modafinil, Armodafinil, Hydrafinil, Flodafinil (Flmodafinil), Modafiendz (N-Methyl-Flodafinil, N-Methyl-Flmodafinil), N-Methyl-Modafinil, Blue N-Methyl-Modafinil, and Eugeroic king NZT.
I took 50mg of Amitriptyline and an hour later, I was asleep all night. The next day, I slept a few more hours. I was d fully alert the third day. Best sleep ever! Thanks sleeping pill!
by CognitiveFuel September 02, 2023
Dibutyl ether is an ether that is used for complex grignard reactions where higher temperatures are needed. Dibutyl ether is good for reacting benzyl magnesium chloride (made from benzyl chloride and magnesium turnings in dibutyl ether) with acetonitrile in dibutyl ether at elevated temperatures. Then reacting it with hydrochloric acid to get Phenyl-2-Propanone. Dibutyl ether increases the yield compared to diethyl ether. Dibutyl ether is produced by reacting butanol with sulfuric acid. The temperature cannot be too high, as butanol could dehydrate into butene (1-butene). The ether must be stored with butylated hydroxytoluene as explosive peroxides can form.
Properties
Chemical formula
C8H18O
Molar mass
130.231 g/mol
Appearance
Colorless liquid
Odor
Fruity
Density
0.77 g/cm3 (20 °C)
Melting point
−95 °C (−139 °F; 178 K)
Boiling point
141 °C (286 °F; 414 K)
Properties
Chemical formula
C8H18O
Molar mass
130.231 g/mol
Appearance
Colorless liquid
Odor
Fruity
Density
0.77 g/cm3 (20 °C)
Melting point
−95 °C (−139 °F; 178 K)
Boiling point
141 °C (286 °F; 414 K)
I reacted benzyl magnesium chloride with acetonitrile in dibutyl ether and hydrolyzed it with hydrochloric acid to get Phenyl-2-Propanone.
by CognitiveFuel January 16, 2023
A speedball is NOT heroin mixed with cocaine. Speedballs don't contain cocaine or Crack. A speedball is heroin mixed with speed (Amphetamine, Ethylamphetamine). It's in the name, stupid. Speed is the Speed part and Heroin is the Ball part. Heroin makes you sleepy and Amphetamine makes you awake and energetic. Don't do heroin! Stick to Kratom! Also, don't do fentanyl. You can dissolve Amphetamine and Heroin in DMSO and put it on your skin and it goes right inside your body. The speedball can kill, but if you survive, you can get super high.
I mixed Heroin and Amphetamine in DMSO and poured it on my skin. It ended up in my bloodstream and I got super high. This is a great speedball.
by CognitiveFuel January 12, 2023
2-Chloromethylthiophene is used as an intermediate to 1-(2-thienyl)-2-Propanone.
In a 2-l. beaker surrounded by an ice-salt bath , and fitted with a mechanical stirrer and a thermometer, are placed 420 g. (392 ml., 5 moles) of thiophene and 200 ml. of concentrated hydrochloric acid. A rapid stream of hydrogen chloride is passed continuously into the mixture with vigorous stirring. When the temperature reaches 0°, 500 ml. of 37% formaldehyde solution is added at a rate that will permit the temperature to remain below 5°. The addition requires about 4 hours. When all the formaldehyde solution has been added, the mixture is extracted with three 500-ml. portions of ether. The ether extracts are combined, washed successively with water and saturated sodium bicarbonate solution, and then dried over anhydrous calcium chloride. The solvent is removed by distillation, and the product is distilled under reduced pressure through a 50-cm. fractionating column. The product boiling at 73–75°/17 mm. is collected. The yield is 257–267 g. (40–41%) of a colorless oily liquid.
In a 2-l. beaker surrounded by an ice-salt bath , and fitted with a mechanical stirrer and a thermometer, are placed 420 g. (392 ml., 5 moles) of thiophene and 200 ml. of concentrated hydrochloric acid. A rapid stream of hydrogen chloride is passed continuously into the mixture with vigorous stirring. When the temperature reaches 0°, 500 ml. of 37% formaldehyde solution is added at a rate that will permit the temperature to remain below 5°. The addition requires about 4 hours. When all the formaldehyde solution has been added, the mixture is extracted with three 500-ml. portions of ether. The ether extracts are combined, washed successively with water and saturated sodium bicarbonate solution, and then dried over anhydrous calcium chloride. The solvent is removed by distillation, and the product is distilled under reduced pressure through a 50-cm. fractionating column. The product boiling at 73–75°/17 mm. is collected. The yield is 257–267 g. (40–41%) of a colorless oily liquid.
I synthesized 2-chloromethylthiophene from thiophene, concentrated hydrochloric acid, and formaldehyde.
by CognitiveFuel January 22, 2024
421 stands for Kratom! 4/21 (April 21st) is national Kratom day. The day where you chug Kratom and get sauced/kratered (buzzed off kratom). Kratom gives you energy at lower doses and enhances mood and relaxation (especially at higher doses). Higher doses is also good for pain relief. Kratom can be taken at any time, but it's cooler to take it at 4:21pm.
by CognitiveFuel December 18, 2022