Short for 'And what are you going to do about it'

A reality show person who changes behavior, usually more obnoxious, when the cameras are rolling.

A nice way to tell someone that their incessant display of affection for their dog or cat is causing you embarrassment as one who is forced to watch such display

When something drastic happens in your life that causes you to take a serious financial loss. Economic downturn on a personal level.

the part of youtube where one encounters very odd videos, such as the retarded running horse, retarded dog, and drunk squirrel.

Having to use a public restroom (for #2) that has either no lock on the door to said restroom, or no lock on the stall you are using.

To stick your hand in your pocket and scratch your balls.