When a woman is having penetrative vaginal intercourse with a man, and Thanos snaps his fingers so that only the guy disappears, the ash residue that is left behind from his dick, will cause a condition called vashgina inside the ladys pussy.
"Ricky and i were having sex last night when the Thanos snap happened, and now hes gone and i'm left with a horrible case of vashgina!"
While our lifespan is the number of years we will live, our healthspan is the number of healthy years we will have and our sexspan is is the number of years we will continue to be healthy enough to continue having an active sex life.
A lighthearted reaction upon receiving disappointing news of some sort. Usually something that isn't a particularly a big deal, esp. when it primarily affects someone else - sort of a mild schadenfreude. Sometimes doubled or tripled, and possibly said in a sing-songy voice for added comedic effect to imitate a muted trumpet, which is how the meme originated.