powder smack Share definition Flag The act of dousing one's hand in powder such as talcum or baby powder and then smacking a bitch ass trick in the mouth. My bottom bitch came up short on my funds and I had to powder smack the bitch ass hoe! powder smack by Cleveland Post March 5, 2014 0 0 Get merch Get the powder smack mug. Buy Now — $32.95 See more merch