"Pootis" is a quote from the Heavy, from Valve's free-to-play Team Fortress 2 game. The original quote by said Heavy is "Put dispenser here". However, due to his accent, it appears to sound like he is saying "Pootis spencer here". Therefore, people have grabbed the word "Pootis" from this, thus creating an internet meme.
Meaning 1 : "Pootis" or "Pootus", ~noun, Phu-tosthe meaning of life.
Meaning 2 : A Phrase removed from TF2's Put Dispenser Here. Used by the Heavy Weapons Guy of TF2
Example 1 :Scout: Yo Heavy Heavy: What?
Scout: Define "Pootis"
Heavy: "Pootis" or "Pootus", ~noun, Phu-tos the meaning of life.
Example 2: Heavy : Put Dis/penser here.
The phonetic spelling of the way the "Heavy" character from Team Fortress 2 requests a dispenser, (an in-game item built by the Engineer character that gives health and ammo to nearby players), saying "Put dispenser here" though his accent makes it sound rather difficult
A special skill of advanced TF2 hoovies where they first of all equip either the Stock, Saxxy, Apoco-fists or Holiday punch, taunt, and quickly say the "put dispenser here" voice-line. This gives the effect of, if done right, saying "Pootis Pow"