nintendo thumb 

A condition marked by blisters, which come after a long session of playing a video game. So named because the NES Controllers caused this condition frequently.

I beat Renegade, and all I have to show for it is a bad case of Nintendo thumb.

nintendo thumb by Wadatah May 23, 2005

nintendo thumb 

The numbness of the thumbs and index fingers commonly occurring after hours of game console use.

"Those fucking Covenant sonofabitches are giving me nintendo thumb!"

nintendo thumb by Keith November 29, 2003