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lowest form of life 

Concerning human beings, the worst of the worst. spineless, backstabbing, two faced individuals, combined with the most modicum of intelligence.
They often end up as middle managers of popular food chains, or jailers. They are useful at always having good information on who the scapegoat of the day is, but not to be trusted alone with pets or children.

The most defining attribute of such a person is a natural illusiveness they dont seem even to be aware of.

Its that person who seems well enough accepted by all and yet you feel ill at ease when they are around.
If you want to see the lowest form of life on earth, just go hang around a prison during shift change.

Mark Twain
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Lowest Common Denominator

A particular type of obnoxious person one encounters in extremely large groups, or where everybody is universally included. Because there are so many people, there is a significantly higher probability of idiotic people.
Facebook comment sections are terrible. It's just giving voice to the lowest common denominator.

Lowest Animal 

This is a human that is the most disgusting creature to ever walk the face of the earth. Not only do they smell bad, but they act stupid, and sleep around with grunge ugly people. Most commonly associated with males.
Ted: Man, last night I got this girl drunk and took her back to my place to have sex. Then I farted in her face! I'm so cool.

Nathan: No dude, you're the Lowest Animal.
Lowest Animal by GulleyBreeze October 19, 2010

lowest of keys 

Involved with low key. To keep something really quite; never talk about it.
On the lowest of keys tho, I think she's a bitch.
lowest of keys by Gswizzle February 12, 2015

Lowest Common Denominator

1. The number underneath in a fraction after simplification

2. A dumbass or a group of dumbasses
1. "I got half marks in that maths test because I didn't simplify to the lowest common denominator"

2. "I got into a fight with a group of the lowest common denominator, mate"

Lowest Common De-nom-nom 

when a group gathers and tries to compromise on an appropriate dining spot, the differences in desired cuisines leads to everyone settling on a standard diner that nobody wanted to eat at in the first place. They have settled for the lowest common de-nom-nom
Joe- who's up for chinese?
Steve- nah man. im in the mood for mexican
Danny- no thanks. I'm not in the mood for diarrhea. Italian?
Steve- Had it last night. besides, im allergic to wheat. Theres a nice steak joint down the block...
Joe- Im vegetarian, so fuck you. What about bon cuisine, down on 5th?
Danny- fuck you rich boy. I can't spend $40 on a piece of salmon. Denny's?
Joe + Steve- fuck you.

Joe- Fuck it. we're going to marge's country diner.

Steve- fine. they got everything and they're dirt cheap
Danny- like your mom. I guess. It seems to be the lowest common de-nom-nom.

lowest form of intelligence 

being really ridiculously unintelligent or stupid
the lowest form of intelligence known to man - claire