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1. acronym for Laugh Out Loud + sob -- an expression for something that makes you lol and cry at the same time.

2. acronym for Laugh Out Loud, Son of a Bitch. An expression of bitter anger over something funny.
That fatal clown car accident made me lolsob-- clown cars are funny but my best friend was driving.
by duenna9 October 12, 2009
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