This alternative expression for 'lol' was invented and popularised by Australian comedians Anna+Mae. It's an acronym, with the letters meaning respectively: "Laughing Almost Manically so Everyone Stares", and is generally used during IM conversations to indicate that one is laughing so much as to attract the attention of anyone in the vicinity.
As stipulated by Anna+Mae during their 2009 show "mirror", LAMES is only to be used in situations of genuine hilarity.
during an IM conversation:
A: "Hey, check out this youtubelink."
L: "LAMES!"
A: "I know isn't it hilarious???"
L: "Yes!!! But now everyone is staring at me cause I'm at an internet cafe and just laughed really loudly :("
A severe sickness related to ones social health. This disease is characterized by both boring and lazy attitudes towards anything related to interacting with people and staying by themselves every night of the week. People with this disease will typically create elaborate lies just to get out of spending time with friends, some of those include; Creating a fake job, fake significant others, fake family reunions, and fake financial issues among other things.
Andrew's Lames Disease must be flaring up, he told us ain't coming to play ball because he has to work but I heard he got fired weeks ago.