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The breeding of people/ animals/ plants that are closely related to each other (first cousins or even closer), thus keeping the genepool weak and leaving them vulnerable to various health problems, mentally and emotionally as well as physically.
Purebred dogs and royalty are notorious for inbreeding; to keep the line "pure" then they are only allowed to procreate with their "own kind", even when offspring are stupid, sickly, deranged, ugly or any number of things.

Carlos II of Spain was the end result of the Spanish Hapsburgs; his parents were uncle and niece and both were highly inbred. Carlos was deformed, retarded, delicate, and had an extended infancy and premature senility. He was married twice, but he was impotent and sex was beyond his abilities.

Plants can be inbred, too; bananas of today are very different from those of three generations ago and often lack the genetic diversity which would keep them healthy.
by Lorelili January 15, 2011
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Aug 5 Word of the Day
When your so pissed off from losing multiple amount of games that you play worse and worse till your so pissed you begin leaning over your keyboard screaming over every little mistake you make and complaining about gaming imbalances

(Common in Starcraft II)
"Why is johnny screaming at his computer"

"He lost a few games of Starcraft II, I think he is Tilting"
by Lashley1337 February 14, 2012
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2
The breeding of two animals who are related to each other.
by M February 19, 2004
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3
How graduates and fans of Auburn University (a.k.a Cow College, The Barn, Bama Poly, The Silo, Redheaded step-child) procreate.
EaglesKill05 practices inbreeding with his mother. The result is a child with huge ears, 12 toes, 8 fingers, and no balls.
by Roll Tide Roll October 20, 2005
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