ho muffin Share definition Flag A short home-wrecker. She can be young, older, pretty, or uglier. Watch out! She's quick to steal your man! See that girl over there? She is such a ho muffin! She's broken up so many homes it's not funny! ho muffin by peachpie88 September 10, 2011 0 0 Get merch Get the ho muffin mug. Buy Now — $32.95 See more merch