Top definition
To go on the television-show of Oprah Winfrey.
Interviewer:"So you had chemo that cured your hepatitis C; that must have been hard on you."
Steve:"Yeah, I'm thinking of going Oprah with it."
by Swords&Scoucerers October 12, 2006
Get the mug
Get a going Oprah with it mug for your mate Sarah.