empty set Share definition Flag 1.The empty set is not the same thing as nothing; it is a set with nothing inside it. It's a mathmatical term. 2. The head of a stupid person. Kevin is such an empty set. He's got nothing going on upstairs. empty set by Sandi68 April 28, 2006 0 0 Get merch Get the empty set mug. Buy Now — $32.95 See more merch