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When a girl only can do one thing to your penis orally
I want some drain-o from her
drain-o by Darnell Black June 7, 2005

Missouri Drain-O 

To perform anal sex while using Sanitizing gel as a lubrication shortly after defecating.
Guy: "O baby, you just took a crap? Wanna do a Missouri Drain-O real quickly to clean it out?"
Girl: "I'd love to"
Missouri Drain-O by mexichode6969 January 18, 2010

The Drain-o 

Its when your having sex with a chick doggie style over a toilet while she's throwing up from drinking to much.
I gave that chick the drain-o last night after the party.
The Drain-o by Namesayer March 22, 2009

Drain Out 

A verb meaning to abstain from smoking marijuana. To take a break or lessen yourself from getting high. The period in which someone refrains or stops their intake of marijuana. Extracting marijuana and THC out of your sytem. To bring your senses back to normal.
Homie#1: Aye bro you tryna hit this cart in the bathroom before lunch?
Homie #2: Nah bro I’m too fried rn and I’m tryna drain out.
Homie #1: Alright bet
Homie #1: Yo dawg! I’ve been drained out for two weeks can I chief on your blunt?
Homie #2: HELL YEAH MAN! it’s pretty SMACK!
Drain Out by Young Walt April 2, 2019

Drain on the Economy 

Someone who draws a living off people without offering service or making a product. A bum.
After college, I spent 8 months on my parents' couch wondering if I was a drain on the economy

Drain of shame

The piss after fornicating with such a disgusting person that you feel horrible regret during it.
Dude I was your wingman last night, and after securing your prize, during my drain of shame she opened the door and force me to give her a golden shower.
Drain of shame by Bolt Z September 26, 2019