When you funnel an entire 2 liter of Diet Coke into your asshole, Followed by a whole living lobster (no standard procedure exists get creative). Allow these two components sit for an extended period of time, until a danger is presented to you, It is only now that you insert mentos into your anus causing the diet Coke to fizzle rapidly, which will then turn your colon into a makeshift cannon of sorts, furring the lobster at foes at a high velocity.
While our lifespan is the number of years we will live, our healthspan is the number of healthy years we will have and our sexspan is is the number of years we will continue to be healthy enough to continue having an active sex life.
A lighthearted reaction upon receiving disappointing news of some sort. Usually something that isn't a particularly a big deal, esp. when it primarily affects someone else - sort of a mild schadenfreude. Sometimes doubled or tripled, and possibly said in a sing-songy voice for added comedic effect to imitate a muted trumpet, which is how the meme originated.