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Anyone who is unduly enamoured of the Twilight books/movies. Such individuals are typically characterized by their obsession with Edward Cullen, the main protaganist of the series, and lack any rationality or intelligence when it comes to the subject.
Edward Cullen Look-Alike: Hello.
Twisexual Girl: Oh my God, you look just like him! (immediately bends over)
Edward Cullen Look-Alike: *fap* *fap* *fap*

Edward Cullen Look-Alike: Hello.
Twisexual Guy: Oh my God, you look just like him! (immediately bends over)
Edward Cullen: *fap* *fap* *fap*
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Someone who wants to have an orgy with the cast of Twilight
I'm a Twisexual
twisexual by greenday22 May 18, 2011
girl: "i love edard cullen!!"

guy: "what a twisexual..."
twisexual by Lehmon February 22, 2009
A male who's into the twighlight series for one reason only... to pick up chicks
Mary: OMG your into the twighlight series?

Dave: Sure am... wana hook up?

Mary: OK

Dave: who'd have known being a TWISEXUAL would pay off
TwiSexual by Twisex January 30, 2010
loving Team Edward and Team Jacob aka wanting to bang edward and jacob
J: Last night while with my boyfriend, I was thinking of both Edward and Jacob...Does this mean I'm twisexual?

Ayesha: I mean...it's bad for you...i already twifucked both of them
TwiSexual by Ayesha721 July 10, 2010

taesexual 

Only being attracted to Kim Taehyung from kpop group BTS
Person 1: "omg that guy is totally into you, you should go out with him"
Person 2: "sorry, i'm Taesexual"

Person 1: "Uh what?"
Person 2: "I'm taesexual"
Person 1: *backs away slowly*
taesexual by Band_Trash2259 July 15, 2018

taysexual 

A person who is straight but gay for Taylor Swift
I didn't know I was taysexual until I saw her live in reputation stadium tour.
taysexual by cansuu May 20, 2020