Tit Acne Share definition Flag also known as "TA", Tit Acne is when a female developes an acute case of acne (or zits) on the breast area. Damn Amanda, you better do somethin about that tit acne before Brian dumps your ass. Tit Acne by Bonanza88 June 20, 2008 0 0 Get merch Get the Tit Acne mug. Buy Now — $32.95 See more merch