What you succeeded in doing when you failed to understand local natives' warnings during a visit to Cols and went noisily/splashingly wading in a creek that is inhabited by fearsome-toothed red-colored anglerfish-like predators.
If you don't want your gravestone to read, "Missed the point --- pissed the moint", you should closely listen and comprehend what your intergalactic tour-guide tells you about the dangerous plants and animals on a particular planet or asteroid that you're planning on visiting.
While our lifespan is the number of years we will live, our healthspan is the number of healthy years we will have and our sexspan is is the number of years we will continue to be healthy enough to continue having an active sex life.
A lighthearted reaction upon receiving disappointing news of some sort. Usually something that isn't a particularly a big deal, esp. when it primarily affects someone else - sort of a mild schadenfreude. Sometimes doubled or tripled, and possibly said in a sing-songy voice for added comedic effect to imitate a muted trumpet, which is how the meme originated.