Samsonite syndrome Share definition Flag people who tan WAAAAAAAY too much and have leathery skin like a suitcase. did you see that old cougar at the pool? She totally has Samsonite syndrome, all she needs is a handle. Samsonite syndrome by tamtamcracker August 10, 2009 0 0 Get merch Get the Samsonite syndrome mug. Buy Now — $32.95 See more merch