A reduplicative diminutive of oy expressing frustration or exasperation.

Variant spelling: oi yoi yoi
Slipping down in his hospital bed, Grandpa Vince says upon seeing his son, "Oy yoi yoi."

Boston Legal. The Good Lawyer. Season 3, Episode 16. Teleplay by David E. Kelley.
Bethany Horowitz: "Oy yoi yoi. Just do it."

Painting by Roger Hilton at the Tate Gallery in Britain: Oi Yoi Yoi (1963)
by Paleohippie June 11, 2008
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A phrase, origin of which is in Hebrew and now one of the most popular phrase in Israel. It's equivalent to "stop complaining like a baby" but much more cynical.
it's usually used when someone complains about unimportant things.
She: I'm 40, single, ugly and got fired today.
Me: I hear what you're saying and it sounds like Oy Yoy Yoy! I'm so miserable! No one wants me! I'd rather kill myself!
by Burgi March 15, 2005
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