A phrase usually said by Chicagoan's meaning...
1) To be out making cash
2) To be wildin and having fun; yolo
3) to be deep with your niggahs
4) having a going time out in these streets
Short-hand for the word floccinaucinihilipilification, meaning the estimation of something as valueless (encountered mainly as an example of one of the longest words in the English language).