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Abbreviation for "Outta Sight, Outta Mind". Indicating that interest in someone or something disappears when that person/thing is not present.
What's up with him? Yesterday he was so into me. Today it's OSOM.
OSOM by 5th dentist June 11, 2009
An acronym that means Out of site out of mind. When you hide away from your boss at work to get out of doing more work than you have to.
Aye man you osom right now the boss is looking for you.
Osom by Jaybwallen October 2, 2019

Osomatsu 

Osomatsu is a eldest brother of the sextuplets of the anime Osomatsu-san. He is famous for playing pachinko, being silly, rubbing his nose with his finger and doing the money sign with his hand. He acts like the leader sometimes but he is actually a cute dork. He usually wears a red jumper and jeans.
Person 1: Who is ur fave Matsuno brother?
Person 2: I love Osomatsu!
Osomatsu by Breanime145 August 9, 2017

Osomatsu-san

The mind-fukery of an anime that came out in 2015.
English name:: Mr.Osomatsu
To celebrate Akatsuka Fujio's 80th birthday, Osomatsu-san continued the adventures of the Matsuno sextuplets from Akatsuka-sensei's manga and anime Osomatsu-kun.
As for its contents, Osomatsu-san is about the Matsuno sextuplets' lives as twenty-something virgin NEETs. Interesting right?

First you have the "miraculous idiot" Osomatsu, then the "cool idiot" Karamatsu, the "reasonable idiot" Choromatsu, the "pitch-black idiot" Ichimatsu, the "of-another-dimention idiot" Jyushimatsu, and finally the "good-at-letting-others-pamper-him" idiot Todomatsu.
Episode count(not including extras):: 25
Genre(ep1-23 & 25)::Comedy. Episode 24::Suffering

This anime that was thought to be one of those that would just slip under everyone's radars and be "that one anime that I never got to watching" is now one of the most popular anime in Japan. So y'know...why don't ya go watch it?
Osomatsu-san is an anime.
I honestly don't know what sentences you would use Osomatsu-san in.
Osomatsu-san by Ichimat June 16, 2017

osoma bin ladin 

little pussy ass bitch who hides in holes smaller than his penis
osoma bin ladin by bob April 16, 2004
The way NEW YORK from I LOVE NEW YORK spells 'awesome'
she's not leet; she's just dumb as fuck
G for Great
O for outstanding
O for osome
D for DAMN NEW YORK IS A DUMB BITCH
osome by Ryan..the kid January 10, 2008