Mouse in the House 

When a basketball player has a much smaller defender guarding him in the post.

Player: Mouse in the House

Mouse in the House by and1jsheng June 20, 2013

Mouse in the House 

When you have a small problem that is supposedly easy to fix, but can’t due to how hard it is to explain the problem

Biology teacher: You have a missing cell lab assignment in my class
Me: But I just turned it in yesterday
Biology teacher: Yeah, I didn’t get any assignments from you
Me: Did I forget to put my name on my paper? Did I turn it in the wrong time?
Me: Darn it. I got a mouse in the house

Mouse in the House by anonymouslapras2783 September 12, 2019

Mouse in the house 

A small booger which is visible at the forefront of your nostril

E.g. Jeff, you have a mouse in the house. Here's a tissue.

Mouse in the house by Vancitygirl January 10, 2012

Mouse in the house 

Mouse in the house is when your penis is too small to have sex with a girl, so for her pleasure, you tie the tail of the mouse to your small penis and have sex with her.

Dude last night I gave my girl a mouse in the house, it was rad.

Mouse in the house by Tusen2KxX December 5, 2017

Mouse in the House 

When you're suspicious or know that your gf/wife is cheating on you with another man. Dick = Mouse, Vagina = House

Bro: Yo man I just saw your wife out with this dude and kissing and hugging!!!

Capt'n: Dammit man! I have a Mouse in the House.

Mouse in the House by Dudeyobruh July 19, 2017