motherzucker Share definition Flag Synonymous with motherfucker because Jeff Zucker at NBC is the dumbest motherfucker in television. That dumb motherzucker tried to bump Conan's Tonight Show to 12:05. What the Zuck? motherzucker by Randrage January 14, 2010 0 0 Get merch Get the motherzucker mug. Buy Now — $32.95 See more merch