An almost sarcastic response to something so seemingly simple you shouldn't have to ask the question to begin with. Could also be an affectionate term meaning again that the answer should be obvious but you just missed it. It is said so quickly, it almost sounds like one long word.
"He's owes me money that's why you haven't seen him. You don't know? He better not come around here".

Guy to his girl "I love you shorty, you don't know?"
by Isis4aday May 20, 2008
"You don't know me" is an incredibly brilliant statement that you can resort to when Mr. Jack Daniels is making it harder for you to say things that make sense.
Cop: Sir, have you been drinking tonight?
Me: You don't know me.
by S4lutDude! December 29, 2010
A: Hey, dude! 34 that on Photoshop.
B: 34?
A: Yeah, make that steamy.
B: Steamy?
A: Dude, you don't know jack about imaging, don't you?
by Deuces High March 10, 2011
You don't know anything. You don't know what you are talking about. Similar to squat and diddley. There is also a board game and a movie called "You Don't Know Dick" but the saying is considerably older.
If you had to look this up, you don't know dick.
by terrorint December 14, 2015
Jerry: Let's bring out the fat and ugly sluts!

*JERRY,JERRY, JERRY!*

Sluts come out screaming, "You don't know me! You don't know me!" while audience is booing with disgust.
by Carlito October 7, 2004
An expression often yelled by voluptuous women in heat. Meant to convey their rebellious sass, invincibility, and general rejection of white male society. The expression is often utilized in day time talk shows based featuring bootylicious women on quests to find their respective "baby daddies." Warning: Do not mess with this species of female. She will shank you. Also, the phrase rarely makes contextual sense.
Todd: Hey babe, let's go back to my place.

Monica: I ain't yo' ho. I won't give it up that easy.
Todd: Baby, can't I just put the head in?
Monica: YOU DON'T KNOW ME! YOU DON'T KNOW ME! YOU DON'T KNOW ME!
by SleezyC1234 May 26, 2009
An extremely popular video trivia game where the categories are outrageous, the questions are hilarious and the host makes fun of you when you're wrong! Everyone I know goes crazy for these games.
Have you played today's Daily DisOrDat game on the You Don't Know Jack Website?
It's called:
Spank Me! Spank Me Per the Geneva Convention!
Me DisOrDat you long time.
And it tests your knowledge of two very important topics!
by Marcy33 December 22, 2006