Lake Shore Drive. A road on the east side of Chicago that runs almost parallel to the shore of Lake Michigan.
Made famous outside of Chicago by the band Aliotta, Haynes, and Jeremiah.
Cruising on LSD is only legal in Chicago.
by Illinois Joe October 8, 2004
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Yo, I got a 2 way LSD that be sending my S13 sideways down the track!
by DeeZNutZ July 29, 2003
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n. synthetic drug. (see above)

also known as acid.

Can be taken orally, or through the eyes in the form of eye drops.
(no example for this)
by The Light of Reason February 20, 2005
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LAKE SHORE DRIVE for all the chicagoians
by TRACYZ July 12, 2004
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Stands for long slow distance. What runners do to build endurance or train for a long distance event, like a marathon.
Runner #1: Man, track season finally ended, and all my tough interval workouts are over.

Runner #2: So you're done with speed?

Runner #1: Yup. And I'm ready for LSD.
by Bombadier General June 10, 2008
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Limited Slip Differential - a differential that is designed to work adequately when one of the wheels is slipping on the road.
Ken, where's the LSD? I have a race tonight!
by FMRommel March 14, 2019
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Example: "Oh hi Fred!"
"I just tripped on LSD."
"Oh. Is she okay?"
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